Usefulness of PGI2 analog-Iloprost for ischemic heart diseases.
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PGI2 as a Regulator of Inflammatory Diseases
Prostacyclin, or PGI(2), is an end product derived from the sequential metabolism of arachidonic acid via cyclooxygenase and PGI synthase (PGIS). The receptor for PGI(2), IP, can be found on a variety of cell types and signaling through this receptor exhibits broad physiological effects. Historically, PGI(2) has been understood to play a role in cardiovascular health, specifically having powerf...
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1987
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.18.99